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Methodology Questions >> How to >> Unkwown character
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Message started by Olivier Fedrigo on Mar 27th, 2006 at 5:26am

Title: Unkwown character
Post by Olivier Fedrigo on Mar 27th, 2006 at 5:26am
Hi,

I was wondering how HyPhy deals with unkown character. Does it consider it as a "?" or is the column ignored?

ex: other characters than ACGT-? such as N

Thanks,

Olivier

Title: Re: Unkwown character
Post by Sergei on Mar 27th, 2006 at 7:30am
Dear Olivier,

HyPhy uses the standard IUPAC (Multimedia File Viewing and Clickable Links are available for Registered Members only!!  You need to Login Login) table to deal with ambiguities (in nucleotide data). All of those are understood and analyzed. See a section in the first chapter of my disseration Multimedia File Viewing and Clickable Links are available for Registered Members only!!  You need to Login Login for exact details. HyPhy is NOT case sesnsitive.

If an unknown charater is encountered, it is ignored in that sequence only. You can also augment the standard table to deal with any character you like. This can be done directly in the datafile, by including an appropriate header.

Cheers,
Sergei

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