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HYPHY Package >> HyPhy feedback >> identical sequences
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Message started by ciccioriccio on Feb 8th, 2012 at 9:12am

Title: identical sequences
Post by ciccioriccio on Feb 8th, 2012 at 9:12am
Hi
I'm a new user and so I'm afraid to make a wrong choice.

I have about 350 sequences from human populations, but removing identical sequences only 3 sequences remain....

I red in your tutorial that identical sequences do not contribute any information except base frequencies.
Can you confirm me that allele/haplotype frequencies are not important for all kinds of DATAMONkey analysis?

Do you think could be a good idea to add sequences from others Primates?

thanks very much

Rob

Title: Re: identical sequences
Post by Sergei on Feb 8th, 2012 at 9:53am
Hi Rob,

Most of Datamonkey analyses do not make use of allele frequency; the only two that do are DEPS and TOGGLE. It may be a good idea to add primate sequences, but this depends on what types of questions you are looking at.

Sergei

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