I'm probably just not seeing it, but are these methods explicitly implemented in HyPhy?

If so , what bf do I need to be using in order use them?

If not , anyone have a resource that might help a scrub get started on the analysis ?

Hi Dylan,

There is a standard analysis to fit the general bivariate model to an individual data set (see screenshot); this estimate forms the basis of ESD.
If you run the corresponding processor file, it will generate a postscript file with the evolutionary fingerprint estimate.

I never put the ESD calculation scripts into the HyPhy distribution: they exist as standalone files. Do you want me to dig them up and send you the files?

Sergei

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If it wouldn't be too much trouble I'd greatly appreciate you digging up the old scripts.