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Datamonkey Server >> Datamonkey feedback >> DEPS http://www.hyphy.org/cgi-bin/hyphy_forums/YaBB.pl?num=1354540004 Message started by perry on Dec 3rd, 2012 at 5:06am |
Title: DEPS Post by perry on Dec 3rd, 2012 at 5:06am
Hello!
Another couple of questions... As far as I understood, MEME is suitable for detecting diversifying selection, whereas DEPS is devised for directional selection. I noticed that DEPS has been mostly used for studying viral populations. My question is whether it is also suitable for inter-specific comparisons (e.g. To identify residues that evolve under directional selection in a phylogeny of mammalian genes). In this case, how do sites identified with DEPS relate to those identified using methods that do not specifically model directional selection (e.g. PAML M8)? Thank you so much! Perry |
Title: Re: DEPS Post by perry on Dec 6th, 2012 at 4:00am
Yes, thank you very much!
Perry |
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