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Modeltest step by step? (Read 3925 times)
qiang
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Modeltest step by step?
Oct 27th, 2006 at 9:14pm
 
I am a new user.I want implenment Modeltest in PY-PHY from multiple nucleotide  sequence alignments.It maybe need a tree file,but I do not kown how to create it.
  EmbarrassedIt's so stupied,but I hope you give me some help.
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Sergei
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Re:  Modeltest step by step?
Reply #1 - Oct 27th, 2006 at 10:03pm
 
Dear qiang,

HyPhy already has an implementation of ModelTest. You need to go to Standard Analyses (which is found under the 'Analysis' menu in GUI versions), select ModelComparison, and then choose ModelTest.bf

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Sergei
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qiang
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Re:  Modeltest step by step?
Reply #2 - Oct 28th, 2006 at 9:37pm
 
hi,seiger
thank you,i have got it.
but using the selected models , i want to  implemente likelihood rate test for a significant deparcrture from the hypothesis of a global  moleculer clock.How do I do?

thank you for your attention!
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Sergei
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Re:  Modeltest step by step?
Reply #3 - Oct 30th, 2006 at 11:36am
 
Dear qiang,

StandardAnalyses>MolecularClock>MolecularClock.bf will do this.

Cheers,
Sergei
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qiang
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Re:  Modeltest step by step?
Reply #4 - Oct 31st, 2006 at 6:03am
 
"-2(Ln Likelihood Ratio)=416.386
Constrained parameters:31
P-Value:0"

I am not good at statistics.How about this result? Is it reject moleculer clock assumption?

Thank you very much!!
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Sergei
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Re:  Modeltest step by step?
Reply #5 - Oct 31st, 2006 at 6:09am
 
Dear qiang,

Yes. Low p-value = high significance of your result (i.e. you reject the null hypothesis, in this case molecular clock).

Cheers,
Sergei
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qiang
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Re:  Modeltest step by step?
Reply #6 - Nov 4th, 2006 at 3:49am
 
seiger,thank you very much.I had worked out!
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