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DEPS analysis (Read 1531 times)
Nobu
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DEPS analysis
Nov 18th, 2009 at 4:43am
 
What is the difference between the HIVBetween and HIVwithin substitution matrices? I want to run DirectionalREL.bf on HIV longitudinal data pooled from different individuals infected with the same HIV subtype.
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Sergei
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Datamonkeys are forever...

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Re: DEPS analysis
Reply #1 - Nov 18th, 2009 at 12:36pm
 
Hi Nobu,

The HIV-between model was inferred from a training dataset comprising population level (bulk) sequences from multiple HIV subtypes and genes and HIV-within - from many clonal sequences (one data set per patient). Run protein model selection on your data and see which of these two is more appropriate (you can do this on datamonkey).

Sergei
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