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BS-REL update (Read 4060 times)
lun
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BS-REL update
Jan 17th, 2013 at 12:45am
 
Dear Sergei,

Can I ask if BS-REL in Datamonkey has been updated?
As BS-REL could detect episodic diversifying selection in my dataset in Feb, 2012. But now, no branches found to be under episodic diversifying selection when I re-analyse it using the same set of alignment.

Best regards,
lun
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lun
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Curious HyPhy user

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Re: BS-REL update
Reply #1 - Jan 17th, 2013 at 2:49am
 
And the episodic selection is reproducible using HYPHY 2.1.2.
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Sergei
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Datamonkeys are forever...

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Re: BS-REL update
Reply #2 - Jan 17th, 2013 at 8:57am
 
Hi Lun,

The version of BS-REL on Datamonkey SHOULD be the same, but I'll confirm. My guess would be that one of the two versions does not converge properly.
Do you have a tree on >30 taxa with lots of short branches, by any chance?

Sergei
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University of California San Diego
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lun
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Re: BS-REL update
Reply #3 - Jan 17th, 2013 at 6:09pm
 
Dear Sergei,

There are only 12 taxa on my tree.
I have attached it for your reference.
Many thanks.

lun
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Sergei
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Datamonkeys are forever...

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Re: BS-REL update
Reply #4 - Jan 18th, 2013 at 9:39pm
 
Hi Lun,

Try again please. I've synchronized the Datamonkey version and the standalone HyPhy version.

Sergei
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Division of Infectious Diseases
Division of Biomedical Informatics
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lun
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Re: BS-REL update
Reply #5 - Jan 19th, 2013 at 7:51pm
 
Thanks Sergei,
The results are reproducible now.
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