Welcome, Guest. Please Login
YaBB - Yet another Bulletin Board
 
  HomeHelpSearchLogin  
 
Testing molecular clock (Read 1941 times)
Nick1979
YaBB Newbies
*
Offline


Curious HyPhy user

Posts: 6
Houston
Gender: male
Testing molecular clock
Jul 14th, 2013 at 11:13am
 
Hi,

I am trying to test whether my sequences are evolving under a molecular clock and just looking at one of the results i am under the suspicion that i am doing something wrong. For example below it seems that human and macaca have very different branch lengths but the molecular clock is not rejected



Unconstrained Analysis:
Log Likelihood = -927.267004691088;
Tree myTree=(marmoset:0.124589,macaca:0.0479423,human:0.0258198);


Molecular Clock Analysis:
Log Likelihood = -928.28141233301;
Tree myTree=(marmoset:0.124299,macaca:0.0369108,human:0.0369108);


P-value for Global Molecular Clock Test:0.362617


The example above is based on an alignment of three orthologous non-functional sequences (length 430 excluding gaps) belonging to human, macaca and marmoset. Marmoset is  taken to be the outgroup. I have attached my code and alignment


Thank you

Nicholas



Back to top
 
Multimedia File Viewing and Clickable Links are available for Registered Members only!!  You need to Login Login (1 KB | 1 )
 
IP Logged
 
Nick1979
YaBB Newbies
*
Offline


Curious HyPhy user

Posts: 6
Houston
Gender: male
Re: Testing molecular clock
Reply #1 - Jul 14th, 2013 at 11:15am
 
Frgot aqlignment
Back to top
 
Multimedia File Viewing and Clickable Links are available for Registered Members only!!  You need to Login Login (1 KB | 0 )
 
IP Logged