Welcome, Guest. Please Login
YaBB - Yet another Bulletin Board
 
  HomeHelpSearchLogin  
 
Fixing branch lengths (Read 1973 times)
scherrer
YaBB Newbies
*
Offline


Feed your monkey!

Posts: 8
Fixing branch lengths
May 25th, 2010 at 11:54am
 
Hello,

I am estimating the rates for several alignments from the same species simultaneously, but would like to fix the branch lengths between them.  Is there any way to set branch length as a global variable?

Also, is there any way to get around HYPHY being unable to estimate negative numbers?

Thanks,

Mike
Back to top
 
 
IP Logged
 
Sergei
YaBB Administrator
*****
Offline


Datamonkeys are forever...

Posts: 1658
UCSD
Gender: male
Re: Fixing branch lengths
Reply #1 - May 25th, 2010 at 12:07pm
 
Hi Mike,

Yes, you can fix the branch length -- take a look at Multimedia File Viewing and Clickable Links are available for Registered Members only!!  You need to Login Login

My apologies in advance, HyPhy exposes a lot of the underlying machinery and makes branch length constraints somewhat obtuse.

You can allow negative values for a parameter in HyPhy batch files to remove the (implicitly enforced) 0 lower bound by including the line(s):

Code:
paramaterName :> -1e-25;

 



to reset the lower bound to some (large) negative value.

Sergei
Back to top
 

Associate Professor
Division of Infectious Diseases
Division of Biomedical Informatics
School of Medicine
University of California San Diego
WWW WWW  
IP Logged