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Ga-branch analysis (Read 1355 times)

line YaBB Newbies Offline I love YaBB 1G - SP1! Posts: 5	Ga-branch analysis Feb 6^th, 2008 at 3:13am Dear all, I perform a Ga-branch analysis on small sample and the result gives me 4 branch classes of dN/dS values; three are < or equal to one and the fourth is higuer than 1000. Could you explain me, please, what means this last value? and how can I consider this value? Thank you for your answer, Line
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Sergei

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Re: Ga-branch analysis
Reply #1 - Feb 7^th, 2008 at 10:37pm

Dear Line,

A large value is not uncommon for short branches/small data sets. All that it means is that the branch has (near) 0 synonymous substitutions so the ratio is estimated to be effectively infinite. Take a look at the model averaged support for having dN>dS for that branch as well (it should be 0.95 or greater if there is strong selection signal)

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Sergei

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